Far Cry 3
Finished the story, got all the letters, memory cards, outposts story quests, and most of the relics and some of the item drop off missions. Currently trying my hand at a new save file on the hardest difficulty. So far it seems I really only have to worry about up close combat since enemies can knock all your health down with one gun smack.
Other than that it doesn't seem much harder and enemies seem to have worse aim or are weaker or something, I remember getting my ass kicked by patrols when I first started.
Who cares, tis be a load of fun.