He's definitely meant to be a human... as portrayed by the movie's intents and purposes, but his showing up so far off into the future completely throws out the door any other piece of literature or chronology after the movie's release (or even before, I gotta check). The question comes down to which "chronology" you want to respect? If you choose to accept AvP and AvP:R as part of the rest of the story you'd have to exclude Alien3's "Weyland". If you choose to accept Alien3's Weyland as human then AvP & R go out the window...
I personally would like to advance that somehow he's a clone of Weyland or maybe a really good lookalike great great great grandson... or something...
I really would've liked if directors spent some time to try and respect a chronology and read all on the subject like comics, novels, etc.
Not just have random locations or times... like AvP's pyramid is in the Antarctic and Predators like the heat... what are they doing there... like directors or writers have no respect for the vast literature and movies before their own creations...
Basically he's human and Paul Anderson is douchy douche for placing Predators in the Antarctic, leading us to believe Alien3 Weyland is an android and just plain butchering a possibility to make a better AvP movie... He could've picked any of the comics to adapt to the screen but noooo, he had to make his own crappy tale. On the "Making of..." documentary he said that's what he dreamt of making since seeing the original Alien movie when he was a kid. That was so insulting.