From everything said so far, I'm led to believe the film will be: thematically deep like Prometheus, big in scope like Prometheus, and scary like Alien with the chasing and the gore and the dark atmosphere.
It won't just be the slasher paradigm, but it will still have that stuff. Remember when lindelof said this about the Alien elements in Prometheus, "it'll be an afterthought as opposed to the bricks upon which the foundation is built"? Well I think the Alien elements will not be as sparse as they were in Prometheus but not as prevalent as it is in a usual Alien film.
Instead of the 80/20 New elements:Traditional elements ratio Prometheus had, I'm thinking 55/45 for AC.