I don't know, I can't imagine any situation in which I would like the idea of clones.
I could see them doing something like Cloning Amanda, and that clone being the one you play as, and then later encountering other clones of her, making a huge test out a xenomorph encounter, a while conspiracy. I know I'm being negative here, but the more I think about it, the whole Clone concept just implies things I can't get behind. Maybe resurrection just let that bad taste in my mouth, but there's only so many reasons the narrative of the story would call for clones instead of synthetics or just more soldiers, and I can't think of one scenario that's appealing.
I'm actually okay with the familiar atmosphere. I thought the Colony in ACM was horribly done (not just because it wasn't as movie accurate as I would have liked). In this case I don't guess they're making an exact replication of the Nostromo, which if fine with me. We rarely get to see situations with aesthetics from the first movie, and I always thought it had the strongest atmosphere, right along side those gorgeous sets in Alien 3. Right now I don't care if they create original environments or not, I'm happy seeing those familiar computer screens, glowing things in what might be the medical bay, suits, ect. I kind of hope they would have a lot of the same signs and symbols that were present in the movie, small details like that (the sign of the person floating upside down, that stuff). If this is a ship and not a space station, I'd love you see the bridge, and maybe even the computer room where the Nostromo crew talked to mother.
Oh, and the areas where they were gathering coolant from, and the room (I don't recall what it was, but I refer to it as the Rain room) where Brett was killed. The aesthetics there were great, Giger or Giger like work was snuck into a lot of those shots, and it worked really well. Not asking for the same thing, but if they could tap into the spirit of some of those sets...