It sounds like - thankfully - there will be no more Aliens on Earth films and that the next avp3 will be set in space and most probably set in the 22nd century.
Given 2004 to 2122 is a long time, do you think it's possible to set a post AVP-R Predator novel that wouldn't f'k with the movie timelines. The Preds may be curious as to humans sudden advancement into space. A good author could incorporate characters from all the Pred films. Ms Yutani, Colonel 'what's his name'. A storyline that could interweave with Harrigan, Lex, Dallas etc.....
The Alien novels i've read seem to have a wide scope in regards to movie canon.