I did - but it tended to do bad things, creating unwanted animation offset and transforms pulling my rig to the position of the animation. It leads me to believe that there must be translations as well as rotations in the animation skeleton data.
But this looks good enough using the vanilla animations that are carefully picked. The Xeno runs on 4 legs when he's really in a hurry - and travels on 2 when he's stalking slowly or about to claw someone.
Still the best is seeing him swim, or when he gets ticked off and roars - his little mouth rigged in such a way it between 2 bones so it stretches down and out when the Xeno opens its mouth wide.