That peice of concept art shows the ship attached by a long cooridor to the mound. I dunno if that holds up in the movie but from what i remember it does since the jugernaut comes up between the prometheus and the mound and the head room was in the mound.
Thats the thing about this movie, we dont know if the stuff is the same, we dont know if the goo is one type, we dont know if its holy and weapons at the same time, we dont know if its actually weapons, we dont know where it came from, we dont know anything. If you put context on one peice of it, then other stuff stops making sense.
I mean the simplest explanation is that the Engineers went to the mound for the same reason we did and some other aliens (giant ufo in the beginning) used them for sacrifices and experiments which gave them a trail to a death trap they couldnt figure out.
They walked in, got blindsided by goo trying to make off with the goods, most of them died, they left the door open which built up atmosphere on this crap complex, The last one ended up in his little lifeboat waiting for help, when help came it was a buncha stupid humans asking the same questions they did, he realized he was not only boned but he couldnt let this stuff get loose the same way Janek said.
It totally explains the Engineers and since two forms of human would have went looking for gods power and got screwed over the title "Prometheus" actually makes sense since the problem keeps happening.
Theres nothing in the movie that says the Engineers actually made us, they might have been forced to sacrifice themselves for another race which made us.
The only thing it doesnt explain is wtf the goo is and what connection it has to Xenos. But either way theres no scene or dialog or clincher that says that, or anything else conclusively happened. The most popular theories come from AvP haters who are using the AvP lore to explain the Engineers, thats just as dumb as anything else lol
The more we break it apart, the more logical explanations we will find.