Kinda, yes.
The Cylons were created by man; the 12 colonies of Kobol made robotic servants called Cylons.
They rebelled; the Cylons declared war on their creators, initiating a bloody war.
They evolved; the robotic Cylons make peace with the humans, and retire to find a planet to call home. An ambassador ship is built. Every year, humans send in a representative, Cylons don't. Nobody heard of them in 40 years. After this time period, the Cylons return -- having created biological, infiltrating models that replicate human beings almost perfectly.
There are many copies; each of the new humanoid Cylons is part of a series of models based on a single archetype.
And they have a plan; striking a surprise attack, the Cylons come back to their creators after 40 years and nuke the 12 colonies. The survivors retire within a fleet of starships, including the old Battlestar Galactica. The Cylons go after them.
The series does fit the basic definition of space opera. There is drama and focus on characters and their development throughout its duration; and not only, but it features a theological debate and an abudant social commentary.
I love the series, but much like anything in the media it is not for everyone. It starts with the miniseries, so if you are interested you could give it a watch.