If you include Alien in the Predator timeline, it's not a universe that is co-operative, it has a bleak outlook which wouldn't allow for anything in the vein of Star Trek, which Alien and Predator always aimed to be the opposite of.
Fundamentally they should hunt us.
We'd either wipe them out to near extinction or they would wisely remain in existence, undisclosed hunting us.
They are Predators.