It's pretty much the same concept. Royal jelly turns people into bugmen in A:CM comic series, black goo turns people into weird alien hybrids in Prometheus.
I like what ACM attempted to do, but it was still in that 80's and 90's era mentality of comicbooks in that the story felt very much like a comic book of that era, instead of just a story told through the comic medium.
Same kind of crazy shit happened in DOTS. Where there are ideas I liked (survivors hanging over the dwindling earth populace in sky cities while Aliens massacred everyone below, while a Predator hunts a woman for reasons she cant remember (plus the art for the initial issues was really good) but it devolved into pure 90's comic mess at the end.
Both concepts would be better realized in today's era of comic writing, because todays era fits the movies better. Back then the movies kind of fit the comic formula.
Or maybe DH just couldn't go full Alien back then.
Even though the seemed to be able to with Labyrinth.
If I look at ACM and DOTS as just comics it bothers me a lot less than it does if I keep referencing the source material in my head. Just like if I look at Resurrection as a standalone movie.