No. Ripley shouldn't be related to anyone in the prequels. This isn't the story of her bloodline. This isn't about her heritage. She isn't the f**king Kwisatz Haderach. Trying to connect the prequels to Ripley through family only makes the universe seem tiny and even more about her. Star Wars suffered from this when it revealed that Vader created C-3PO, and that all the clones are Boba Fett's Dad. This is a Lovecraftian horror about humanity's struggle to survive in the face of a terrible extraterrestrial threat, not Ripley's Family Values.