Its very clear now. David despises Humanity and wishes to wipe them out. He is the Engineer in the Derelict who plans to nuke Earth with the Eggs but gets chestbursted. Its the "Creator vs Created" cycle. David ends up having a taste of his own medicine. However, his legacy lives on. He is the heir to the throne of Weyland-Yutani. David's android brothers got the signal and went for the hunt to continue the legacy of their King. This leads us to ALIEN. Perhaps, in the future, Alien 5 will feature Blade Runner crossover. The new trailer shows the same theme: Creator vs Created. These programmed Humans will join the fight with the androids. Alien Runner could go a darker route. The androids ally with the cloned humans and harvest them as hosts for Aliens. Anyways, food for thought but this is where Alien is heading. Brace yourselves.