Alien Isolation has been pretty successful, there's nothing stopping them from doing more and bigger DLC than planned, Maybe we could go to Fury in A:I2. If they do an A:I2 I suspect it would probably be set on LV-426 before the Sulaco arrives (I'd love some Newt DLC for THAT!), simply because it would take quite a crowbar to insert an Alien into Fury 161 either before or after the events of Alien3.
Knowing it is a successful formula would mean the second game could be more expansive than the first game, meaning they could put more time into designing Fury 161 (maybe even USM Auriga or LV-223) DLC maps.
After all, DLC costs money, why should we expect DLC to always only use assets from the main game! back in the day Expansion packs always added a decent amounts of content, now we have got the the point where we expect them to always be re-hashes of the main game.