I don't think Scott plays computer games, but we know Blomkamp not only has experienced 'Isolation', but that it affected him profoundly enough to directly influence and change how he would approach his own project. We also know that Scott is producing, likes the first draft Blomkamp handed in and has apparently talked a lot with him.
While he might not have played it himself, I do suspect, Blomkamp's had his own influence, in this regard and might have possibly showed him a few brief video clips of it to illustrate his points (if only of peoples' reactions to experiencing it). It would explain why the guy's done a complete 180, in terms of not believing the original design can have any psychological impact, to suddenly including them.