Newt wasn't repeatedly finding herself in the same room as one which was actively hunting her.
Dallas showed they can find you at long range with no line-of-sight (as did their locating the Marines from
waaay over in the atmosphere processor). Newt presumably evaded notice because they had either gone into hibernation or were deliberately allowing her to run around to lure fresh prey in. Which strikes me as having a nicely sinister vibe to it...
Either way, '
Isolation' would need a lot of modifying to be turned into a film. It works as well as it did because it's an interactive experience, which you wouldn't have on the big screen.
Stuff like this?
Beautifully rendered... But it's the kind of scene you can work into a larger story. Having an entire film mostly composed of crouching around/hiding in cabinets and creeping in behind synthetics/following the Alien around? I don't think that would work very well.
The other thing is that you shouldn't need to disarm the main character to make the Alien feel like a threat. It should be one, regardless. That's why it worked to have Ripley kitted up with pulse rifle and flamethrower, trying to find Newt through all those darkened corridors. The viewer knew all it would take is one of the things to have escaped her notice and she'd be at their mercy as surely as Apone and co were.