Scott has already gone on record and stated the next movie will feature Engineers returning to find their planet decimated. We also know there's Juggernaut class ships garaged under the city.
Maybe, the returning Engineers will use those ships to chase down David. It's a short stretch to sketch in the details if that's the case; to have an Engineer pilot infected by one of David's creation to become Acheron's derelict.
Engineer in that seat, for sure. Not David.
-Windebieste.
