I got stuck in the hotel basement in TLOU for like two hours until I found a strategy that worked.
I went to the door first, activated the first wave of stalkers, shot them through the opening to the flooded boiler room with my rifle and bow, ran over, got keycard, started generator, pulled out shotgun and finished the two stalkers en route to the keycard door before the bloater figured out where I was.
I did notice that the stalkers spawn RIGHT beside you because I played that sequence so much.