It's likely Wolverine will win but this is doubtful it'll be in continuity.
Marvel does have a history making licensed properties canonical with ROM, Godzilla, micronaughts, Conan, and Transformers. But I don't think this is the place they'll do it since they did that with the mainline book and not a crossover event or storyline. We'd effectively have seen Predators in the marvel universe at large by now if it was mainline continuity. A fight with Wolverine just isn't the place where this would start happening especially when this is something that spans decades and there already being two Predator book launches. We'd have seen them by now and only Star Wars depicted one's armor in the background. Someone in the Predator book would've brought up other aliens like Kree, Skrulls or even Thanos.
What this probably is likely to be is an out of continuity crossover and likely to be the continuity they use if they do any Marvel crossovers in the future. So there's the Marvel universe Predators, and the Marvel comics Predators. With the only real difference is that one can fight super heroes where the other is the Marvel comics run and probably fudging some details as to why a Predator can throw hands with something like the Hulk.