Madness is something you really can't deal with on a rationale level, at least not fully as it is basically a force. Regardless of whether or not one likes the comics, they did show how dangerous Alien cults could be. People tend to focus on the obvious threat of the alien monsters, and not the threats that are amongst them.
Hmm I might be wrong, but I think AVP:E is the only Alien game to feature Xenomorph cults.