At this point in time, you gotta go with the engineer concept.
You can put in a predator or a group of predators in the main role,
and insert some humans but only as supporting roles.
I would go for an engineer facility with the full Giger stuff,
make the opening of the movie that predators engage the facility and scope it out,
we see some interesting things and no doubt with questions.
Then the terror of the engineers or maybe one engineer begins on the predators,
a brutal kill of a predator by an egineer is shown and eventually wiping them all out.
Next up is years later, and a human group finds the facility, they think its left behind, start doing their research and setting up camps,
one of them finds some predator remains and activates a beacon or just activates the arm and the signal is being picked up by other predators who go and investigate.
They find empty human camps with some hiding around, they go further into the facility and finding or one or more engineers experimenting or doing sick things to humans, and at one point they see a human being showerd with the black goo and turning into something...
They also find some facehuggers, different kinds and different colors, maybe at one point a predator takes on of them and drops it on a human and later on offcourse something totally different comes out of the human, because the predator picked a green or black facehugger, what comes out im keeping it to me atm.
