Hadley's sounds like a good choice, but covering all the years the colonists were there without alien contact would be incredibly dull, unless of course the cast and acting was such that you could just listen to them talk over tea all day long. But that's not likely to happen. You'd have to focus on the day to day of regular people, but there could only be so many lost groups of people trapped in a dust-storm, and people cheating on their spouses to make it viewable for even a short amount of time.
Maybe they could focus on more than the colony. Maybe half the story could involve Wey-Yu back on earth. Maybe even skip between different timeframes. Go back alittle in time, and see the company and whatever jerk was responsible send special order 937 to the Nostromo, and watch as Dallas or Ash interfaces with Mother, if that was possible to see it on earth in real time.
But really, it all comes down to one thing. If Hadley's is involved, there has to be a buildup to the xeno outbreak. So there's only so long you can drag it out. You can't just cover 2 decades of nothingness, or however long it was. So if this does move forward, I hope it turns into like a 10 episode series.
How to end it? I don't know. Maybe have the final shot should be of Newt and her family's crawler leaving the compound to investigate the derelict, or Newt crawling into the vents to escape the xenomorphs. Perhaps see a message from the company (or burke) scrolling across a bloodied screen, asking for clarification or awaiting response.
But that's just for Hadley's. I personally would like to see something completely fresh and new. What we may wind up with is an I-Robot style series where the David's, played by a different actor, turn on their human owners. Like bicentennial man meets Covenant.