I have been surprised people have been missing things like that, but then again, we all missed the barbs on the facehuggers fingers for nearly a year until I saw the movie. I feel like we've always been so good about picking apart things things, but this one has stuff flying under everyone's noses!
It's entirely possible I'm misremembering, but I thought that there was a reference to Prometheus in Isolation in the form of a poster on a wall somewhere within the game? I know there's adverts and posters everywhere on Sevastopol, but if I am remembering correctly, the poster was either pinkish or purple-y and it was for a band, or maybe a movie, named The Promethean Fire or something to that effect?
It's also possible that it's a poster in one of the Dead Space games, in which case it wouldn't be referencing Prometheus, but I definitely thought I came across it in Isolation at some point.