Game really deserves a sequel. I'm actually glad I went in without being as hardcore as Alien fan as I am now. I saw the first two movies but it had been a few years and I didn't know Amanda actually dies in her 80s. So the aspect of plot immunity was not something I thought about and I was on the edge of my seat the entire game. Really, I think the ending made me shit myself the most. If you don't know about her immunity, the game ends off on the potential idea Amanda got facehugged, since she wakes up in a nest. Of course we know she didn't but still.
Also, bit of trivia for you, when you blow up the nest you can hear the queen's screech, the devs confirmed that they had a queen but they didn't want the player to think they would have a boss with her so they kept her out of view.