I'll explain how I got Kwaks to work with AVP. The downside to this emulator is that you can't play Aliens or Alien3. But if you need a quick AVP fix, then this does the job.
1/Just download Kwaks from: http://cps2shock.retrogames.com/download.html
2/Install, then move your zip file (un-extracted) for AVP into the folder: winkawaks157>roms>cps2
3/Rename the AVP zip file to avsp
(saving you a step later on)
3/Open the Kwaks program, go to File>Load Game and select the European version of Alien vs. Predator listed as: CPS2/Alien vs Predator (Euro940520)/avsp
4/Click on it and it should boot up.The essential things to get are putting the zip file in the right folder and renaming it to: avsp
Be sure to check the controls under the Game tab. Hope it helps.