It's easy to pick up off after AVPR. All evidence of the xenomorphs is erased so they are still a mystery, but more can be explored with the government trying to learn more about the Predator races.
But that means allowing the egg barfing life-cycle to remain.
Also, it is the only way (or one of the few for now) to establish a solid link with the Alien timeline. Although it's not like they have that particular plan anyway but instead with the AVP concept. But honestly if I were them, I would go for the AVP reboot from the scratch, because:
1. One AVP film is mediocre and the other just horribly bad.
2. The Alien prequels are there, and such movies are canon no matter what.
Indeed, but if it was up to me, I would have the new AVP continuity ignore the Alien prequels as well, because David creating the Xenos, as well as other issues I personally think the Prequels brought, affects the tone and mythology of the Alien too much to keep it in.
Have AVP with its own continuity and its own lore for the Xenomorphs, the best part about it is that each continuity would be unique in its setting and lore rather than just a crossover.