I'm not too bummed about the removal of the friendly Predators and considering how people hated that in AVP, and considering they hate that style of twist humour from Iron Man 3 too it makes sense to remove them, but it still removes Shane's original vision of the film that could have explored Predator habits in a original light.
Plus while the Ultimate Predator could be a entirely different thing, at its core we have seen this set up before with the Predalien and Super Predators. When the Predator is fighting Aliens or other Predators it stops being tense and becomes a Godzilla vs type film. Essentially this is Predator vs Predator 2.
I like the references to previous films being added though, especially AVP as we don't have too many main Predator films to reference honestly, but I want this to be good and successful otherwise we'll be waiting another decade or two for the next reboot.
As a wise man once said: "Hopefully it'll work."