Obviously this is pure speculation. But personally I am kind of hoping that the "friendly" predators (if we can really call them that) are still in the movie. Not because I like the idea of predator and human team up, but I do think having 3 or 4 predators with varying levels of motivation and hostility to the human characters has some cool potential.
You could have the classic / captured predator, who is clearly not friendly, and he's constantly at odds with these other two who seem to cooperate with his intended prey. He might kill them if he didn't think they were his only chance of getting out of the lab or compound. Then, all of a sudden some abomination freak upgrade shows up, and they all realize they're a bit screwed. Sounds dynamic to me. It probably won't play out that way at all, though.
I didn't dig the leaked APC photo, but at this point I don't really know what to expect, and that's creating some excitement. I don't outright dislike anything I've seen in the two trailers yet.
I do think it's odd that the captured predator seems to have the exact same bio mask that the one on the leaked APC photo had.