not knowing what operating system you have , I made a guess.
windowed mode have a sense only if you have win 8
i never see this inussues on win 7 32/64 bit only on win 8 / 8.1
I know that some mouse have a higher sensitivity to 2500 dpi can give some problem.
if your mouse allows you to lower sensivity do it.
try to disables the joystick & hardware cursor from the advanced boot options
alternative changes mouse
remember AVP2 have15 years is likely that your mause's too modern.