Thinking about it a bit, it's interesting that this film is coming off of the heels of films dealing with sentience in "artificial" creations in both the Alien franchise (Prometheus) and Blomkamp's own personal canon (Chappie).
That being said, I don't see that being the thematic focus of this film. I can see him having a lot of fun exploring these futuristic mega-corporations (not just Weyland-Yutani, but perhaps their competitors as well) and showcasing them at both their best and their absolute worst. Blomkamp already did this a bit with MNU in District 9 and TetraVaal in Chappie, but both of those corporations existed in variations of the modern world and, while they held major stock in current events and the government in their own right, they certainly didn't have any real control outside of their country's borders, let alone throughout space. Given their sole focuses (MNU dealt with weapons and alien relations and TetraVaal dealt with building robotic police units) I don't really see them expanding the way WY did, either. We know of WY trying to get their hands on an Alien specimen and terraforming colonies, but there is so much more to that corporation. We see their logo slapped on everything, and there are a lot of interesting directions the company can be taken in.