This is an old idea of mine. I was thinking that a corporate campaign in a Alien/AVP game (or a company-centric game as stated in the title) could drastically differ from a marine one, by putting players in the role of a slimy, backstabbing Burke-type individual.
The corporate campaign would be less about action and more about manipulating human foes, by say killing some of them in secret and pinning it on another one of your foes, unleashing facehuggers on them when they're alone while avoiding getting nabbed yourself, tell them lies, etc.
Against Aliens, you might have to get your hands dirty. But if your character didn't have much military training, he/she might not be able to use guns properly. Their aim might be poor, they might get shaky in intense situations,etc. But if you're a Machiavellian manipulator, you might get some marines to protect you, rescue you, even die for you.
Against Predators, you could be able to avoid fighting them entirely if you downplay your toughness significantly. You could get them to coincidently kill Aliens for you. But if they see you carrying a smartgun and mowing down foes, they'd definitely take an interest. And since Predators would be hard to spot, you'd have to be careful on how you act even in intense situations. If you even accidently hurt a Predator, well, good luck.
Alternately, the corporate campaign could also be a synthetic one, featuring a Ash/David type. Like David, your programming would prevent you from directly harming humans unless you are attacked, so you would have to find loopholes in order to execute a morally questionable, if not condemnable act should your mission require it.