Will the predator actually decloak whenever he takes damage or uses any weapon, even meele weapons? It looked like it in the demo, and that, in my opinion, is not a good idea.
Will the marine, and especially alien and predator, each have proper sound effects from the original movies (i.e. vocal sounds for alien and predator as well as weapons for the predator and marine)?
Playing as the predator, will it be possible to decide which target to lock onto for tracking weapons rather than have the game choose for us? I.e. lock onto the target in the middle of a group of marines rather than having the game autolock on the nearest one.
Can we get rid of homing plasma bolts and simply have the shoulder cannon lead its target and make the plasma bolt move faster like in AvP1?
Will it be possible to shoot limbs off of the marines and predators as well as the aliens, which we've seen already? Can this carry over to multiplayer?