On the note of projects in the "Universe" not directly featuring the Alien, I was very into Prometheus conceptually (despite the execution being very, very sloppy) and would have been open to its sequel moving its trajectory even farther away from Alien (though I wound up loving Alien: Covenant, so I'm more than ok with the shift back that things took there), so I would definitely be open to another film without the capital-A Alien, if it felt appropriate to do so.