While I would love for Predator to join the billion dollar club, it's not realistic. Not unless they plan on a Pg-13 series so audiences can actually see the thing since by nature of it being R-rated your audience is that much smaller. You need to be realistic about horror franchises since they're cheaper to make but they make their money by virtue of it being cheap.
Though Disney could always use them for the comics or games and especially the games since Predator adapts fairly well to videogames. It doesn't need to just be the movies. You also possess crossover potential with any one franchise they own and AVP is still fairly popular given that's how a lot of modern fans are introduced to the character. It doesn't have to be strictly movies and could even go an animated route. Plenty of options Disney has than to just do superheroes.