An A.I Predator seems unlikely but weirder things have happened. I think they did admit they didn't have the time and or budget for single-player but really Predator is at its best when you have Human players and have been pretty open about it being multiplayer only.
Really I think what people are more interested in is playing as the Predator since that's where the more interesting game-play is. So I'd be all for them doing a single-player that covers that since you can give everyone their fix if they can't seem to get it in multiplayer.
