My main issues are the dialogue (which is trying way too hard to emulate the original movie's and failing at every turn), the voice acting (mostly just for Cruz... I mean, what the hell? The temp actor was better), and most of all, the facial animation... because it's non-existent. The mouths barely move, the eyes rarely blink or move, and I haven't seen an expression go beyond default. In this day and age, that's really bad-- last gen bad.
On the plus side, I like how the Xenos move and act, particularly the lurkers (except for when they just stand still on the ground), the score is fan-f**king-tastic (properly emulating both Alien and Aliens), and the environmental design is squee-inducingly great.