One place you could go with any sequel is the death of her brother haunting her and her realizing there's more. That Naru would become far more protective given the threat they face. And that would be in addition to her new role where she's expected to hunt and fight. And that could lead to conflict, she knows how a Predator operates, so her not fighting back to let it ignore them makes sense. However to those who feel superior or just don't know she might come off as cowardly.
That could then lead to Greyback as given when the ships show up, Greyback probably arrived shortly thereafter. Greyback to parallel Naru might be new to the role himself as Elder. And he's probably seen his fair share of hunters die young which is also something you can illustrate with Feral. Given how shortly the ships arrive after Feral's death, Grayback might take the death similar to how Naru did for Tabbe. We have seen Wolf mourn Bull, but Grayback might've actually known Feral. I could imagine Grayback would be looking for whatever Naru took from Feral's body and be out for revenge. Ultimately I could see the two parting ways amicably because they not only have to survive but both would be going through similar journeys at this point in their lives. They'd see a lot of themselves in each other and go the unusual route of gaining mutual respect (respect since I don't see the movies killing a protagonist and Grayback has to survive).
I'd be fine with her fate being ambiguous for a sequel. Not open ended, but that whether Grayback killed her or not would allow Naru to take on a mythology and play with the EU a bit since she could become an in-universe legend allowing her some influence beyond her character's lifespan.
