Aliens had a logical change from Alien, i.e., from an encounter with the alien, with horror created as the creature is slowly revealed, to Aliens, where they thought they were going to deal with only one creature but turned out to be a lot more, and more detail on what happens when they are able to form a hive. The third movie ends Ripley's story effectively, which makes the fourth movie weird because it brings in cloning, hybrids, etc.
The problem for this new series is that the AvP franchise and the prequels complicate matters, i.e., with earlier encounters with both the aliens and the predators on Earth, and more weird stuff, like spores and all that, as seen in the prequels.
Fans can discount the prequels because it looks like they're meant to reboot the franchise, i.e., they're targetting younger viewers who don't know about the first four movies. That also means anything's now possible for future movies, while they follow the prequels and even ignore the first movie movies.
That means if they follow fans the series will have to consider the AvP franchise, and if they follow new viewers what took place in the prequels.