I recently had a look at Fred Dekker's Facebook page and read the following Quote, posted in September 2014:
"Wanted to be in Austin for this, but writing a NEW military vs. monster movie intervened."
Now, since he is not writing any other stuff, this has to be a reference to Predator right? It was also around the time the announcement was made that he's writing the script.
So lets assume the general theme is again going to be Military Vs. Predator, what about the quote from Producer John Davis "You are going to get something you don't expect"? Could we actually be getting a movie with the Predator as the main character, fighting the military? It would also "expand and explore the existing Predator mythology", as Shane Black said.
Of course, we can only speculate, but the quote is interesting.