I really don't see what would be gained by pitting Colonial Marines up against Predators, these days. The US military would be much like them, even today. Smart-guns, no, but smart bullets have already been invented and motion sensors have been a thing for a very long time (the public areas near to Area 51 are famously littered with them).
And, to be honest, I wouldn't give a Predator much of a chance against us... Our technology is already on parity with theirs - if not even better.