I am really looking forward to Prey. It will be cool to see a historical setting of native Americans vs a yautja.
The Comanche were know as fierce warriors so it is fitting that a predator would take interest.
As for people who are upset that it is a woman, I have confidence that they will do her justice. She will not become a Mary Sue or a disney Pocahontas. She will likely be a well fleshed out character. She will probably use her brains and find a way to win. Same kind thing that Dutch did. He was using a bow and arrow too and in the end outwitted it with a trap.
That or at least team up at the end vs a second foe, after earning each other's respect (if it is Greyback since he is alive as of Predator 2).