Stickied this because yeah, it's kind of important. After my initial wave of enthusiasm, I had the time to think some of this through.
Undoubtely, Blomkamp can definitely nail the dry and dirty style of the first two films -- not to mention that he uses a combination of practical and digital effects that are overall very convincing (just look at District 9, one of the best examples of creature effects in a decade). Very probably the new film will feel like a sequel to them, at least visually.
I love both Alien3 and Alien: Resurrection, I really do -- but I am not particularly opposed to a film that starts anew after Aliens at all. It just needs a solid script to be built on. This brings me to the concept art -- which, mostly, looks pretty promising. Love the Queen in the simulated-jungle facility, and the Derelict-type ship in the hangar (which is more accurate to Giger's designs than the ones in Prometheus!). I don't really like Ripley in the 'Alien-suit', however. If that idea remains in the film, my impression on it will be obviously based on its actual role.
Nothing more than wishful thinking at this point, but I would love it if they estabilished the Derelict Pilot as an actual otherwordly being as opposed to a member of the Engineer race. Very doubtful, but that would really bring it all full circle.