In my case, I'd like a super-duper beefed up remake of Alien:Crew Expendable.
One in which the other crew members (Parker, Lambert, Dallas, Ash, Brett) actually star as important roles in the game, not just walk-on/walk-off cameos like the current version. You would have to converse, cajole, argue, threaten, plead etc. with each of their accurately reproduced personalities in order to defeat the alien. It would need some incredible A.I. programming to achieve this (in a non-linear, branching gameplay environment) but there you go, that's my dream.