Yeah, they're keeping a tighter lid this time around, though based on that two-page "leak" of
Prometheus #1 lettering, I think some characters (like Roth) will cross over between series. The Marines of the
Prometheus #1 cover are probably survivors of
Predator: LaD, but we can't really know. Don't forget it's also going to somehow "intersect" with
Fire and Stone, though Randy hasn't elaborated beyond that.
Spoiler
I'm already looking forward to the hardcover collection that comes of this, even though I'm getting all the issues as they come out.