The key is that the "Corporate Timeline" at
www.weylandindustries.com spoils the film more than anything in the trailer and Ridley's Q&A.
Peter Weyland (Guy Pierce) was born in 1990. Prometheus (name of the ship) mission starts in 2073. Peter Weyland would be 83 years old at that time.
Furthermore, Ridley Scott explains in the Q&A that Prometheus' actual mission/landing on LV-426 takes place in the late 2080's - 2090s. This would make Peter Weyland even older, 90 plus years. But Ridley Scott confirms that Guy Pierce is in the film in some shape, or form.
From the "Corporate Timeline:" Year 2065 - Sir Peter Weyland Memorial Library built in Washington, DC.
So I'm guessing Peter Weyland died at the age of 75. But, take a look at this, from that same "Corporate Timeline:"
Year 2071 - Weyland Industries earns patent number 18,364,003 for Method and Apparatus for device able to temporarily restart brain activity of deceased individuals.
Can you figure it out yet?
Now take a look at this blurb on the "Corporate Timeline:" Weyland Industries earns patent number 15,999,127 for Method and Apparatus for an ejectable luxury pod able to sustain one human life for up to 50 years.
And...
Year 2039 - DISCOVERY OF ARCHERON LV-426 - Weyland astronomers discover multiple moons and a ringed planet just outside the Zeta 2 Reticula System, which are possibly able to support life. Weyland expects to travel there within the century.
And...
Year 2034 - Weyland Industries introduces the first FTL-capable SEV (space exploration vehicle).
And...
Year 2028 - Weyland labs in San Francisco discover the body's ability to hypersleep - the complete cessation of life processes, which can be restarted when stasis is removed. The search for a practical application begins.
Do you see where this is going? First, this is DEFINITELY an Alien prequel. Second, it DEFINITELY takes place on LV-426.
Now... Peter Weyland is an old man, dead man. He is/was after immortality, no doubt. He is put into stasis to preserve his body and placed on the Prometheus' mission.
Fassbender plays David 8. Someone who can mimic EVERY human character/trait. Peter Weyland (during his last days) flashed/uploaded his memories/thoughts/secrets, etc. into David 8.
The crew lands on LV-426. They find the Space Jockey science team destroyed. By none other than their experiments with the Xenomorphs. They must have been conducting something on LV-426. This can clearly be seen in the full length trailer. Dead Space Jockeys everywhere. Abandoned ship, etc.
David 8 discovers their genetic secrets. The crew disrupts the Xenomorphs which have killed the Space Jockeys. The crew begins to experience the same effects that have destroyed the Space Jockeys.
David 8 awakens Peter Weyland, using the Weyland Industries "brain restart." Possibly the old man in the wheelchair. He transfers the Space Jockey's transfer RNA, essentially making Peter Weyland into a Space Jockey. This might also explain why the "Albino" looks more humanoid.
Now here is Peter Weyland's goal... The beginning of the trailer is narrated by Charlize Theron and shows a Space Jockey on Earth. She narrates: "A king has his reign and then he dies." This gets a little murky... The Space Jockey either came willingly to Earth to rule, or was stranded and Earth and ruled. All of the pictographs from different civilizations indicated that he ruled the ENTIRE world. So he either created man and ruled him/her, or he ruled an existing race on Earth via his genetic/Xenomorph technology. When his life came to an end (possibly due to that same Xenomorph tinkering), he left information on his home world. Maybe taught man certain knowledge, etc.
I hope you can tell what happens next... Peter Weyland has this theory/information from Shaw. Since he is now essentially a Space Jockey (and with his enormous ego to conquer), he wants to return to Earth and be the king! He wants to rule the entire planet. He has the Space Jockey ship. He has their knowledge. He has the Xenomorph bio weapon (you get it now why Weyland wants this bioweapon at any cost?).
So, Peter Weyland gets into the Space Jockey's exoskeleton. This is their version of a space suit, if you will. Him and David start up the ship. And want to go back to Earth
Shaw figures out the plan and tries to stop them. We can see Vickers confronting and fighting David 8 in the trailer. We can see Captain Janek sacrificing his life and sabotaging Peter Weyland's plan by ramming Prometheus into the Space Jockey ship. Essentially stranding EVERYONE on LV-426. Coward Vickers (Charlize Theron) gets into a lifeboat and escapes right before the suicide collision.
So here's how I think it ends... Peter Weyland/Space Jockey attempts to kill Shaw, Vickers, etc. He is defeated by getting infected by the Xenomorph. Yup, a chestbuster comes out of his chest. What the Nostromo crew find in Alien is essentially their very own CEO Peter Weyland, rotten and petrified after 50 years, or so.
Now who survives? Possibly no one. Or maybe Shaw. Remember this from the "Corporate Timeline?:" Weyland Industries earns patent number 15,999,127 for Method and Apparatus for an ejectable luxury pod able to sustain one human life for up to 50 years.
Just Like Ripley used the Narcissus as her lifeboat. Shaw can use this pod. For at least 50 years. Leaving the possibility for a sequel
I'm willing to bet my left testicle, that I'm at least 90% correct on the plot
This would also explain why so much focus and information is dedicated to Weyland Industries in viral marketing, etc.
What say you?